This is the one thing that I really really miss from TextPad (back when I used Windows).

Multiple Selection is great, but column selection is different, and is a feature that I long for, achingly.

Please Please pretty please can you implement a column selection feature that will help liberate the right hand margin from the tyranny of CR/LF?

I suspect that this is wishful thinking ... ST2 is a text editor, not an IDE... but then again, what a wonderful wish!

... cue daydream about developer heaven ...

Perhaps all you need to do is develop some suitable UI components, expose the API and let the plugin developers do the rest?

... even so, (coming back down to earth) ... this is a big (and not terribly practical) ask ...